Next-Gen Tumor Models 

Patient Mimicking 3D Tumor Model Platforms For Research and Drug Development.

THE PROBLEM

Right now close to 95% of new cancer drugs fail during clinical trials. Drug development has also become slower and more expensive over time in a phenomenon known as Erooms Law, meaning fewer and fewer drugs are making it to market. One of the root causes of these problems is that the tools researchers use, such as 2D cell cultures and patient-derived xenografts, do not accurately depict human biology.

OUR SOLUTION: TUMOR-ON-A-CHIP

Recreate cancer in the lab as patient-mimicking tumoroids.

Applications

Model Biological Processes

Study important biological processes involved in cancer growth, metastasis and drug resistance. Such processes include:

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Vascularization

Angiogenesis

Immune Modelling

Cell-Cell Interactions

Hypoxia

Test Anti-Cancer Therapeutics

Gain more information about anti-tumor efficacy by testing new and repurposed therapeutics on real tumors. Compatible test agents include:

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Chemotherapies

Immunotherapies

Nanomedicines

Angiogenesis Inhibitors

Biochemistry

Tumor spheroids are suitable to a wide range of studies and assay types. 

• Next generation sequencing

• CRISPR

• Western Blot (protein extraction)

• qPCR

• Immunofluorescence

• Metabolomics

• Proteiomics

• Genomics

• Transcriptomics

• Immunohistochemistry and H&E

• Flow cytometry

Rewriting Erooms Law.