The Soft Agar Colony Formation Assay is a powerful method for evaluating the therapeutic efficacy of compounds targeting anchorage-independent cell growth—a hallmark of cancer. By allowing cells to grow in a semi-solid agar matrix, this 3D assay mimics the tumor microenvironment and distinguishes transformed cells from normal ones based on their ability to form colonies without surface attachment.

 

At Apricell, we combine this proven platform with high-throughput analysis to identify agents that suppress malignant growth and restore normal cell behavior.